Buerger’s disease

Synonyms:   Thromboangiitis obliterans (TAO) ICD-9 code: 443.1 ICD-10 code: I73.1 Definition: Buerger's disease (also called thromboangiitis obliterans) is an inflammatory, nonatherosclerotic, occlusive, vascular disease characterized by thrombotic occlusions of small and medium sized arteries and veins in the upper and lower extremities. It is closely related to and initiated by tobacco use. Etiology: Unknown. Tobacco use and periodontal disease are risk factors. Demographics: TAO Read more [...]

Vasculitis – Comparison Table

VASCULITIS: CLASSIFICATION AND COMPARISONS Three tables below compare the diagnoses according to the size vessel involved (determined clinically or by histology or imaging) Small Vessel Vasculitis Diagnosis (by vessel size) Demographic Features  Local Findings Systemic Findings Diagnostic Test(s)a Treatment Leukocytoclastic (hypersensitivity) vasculitis M = F; all ages can be affected Palpable purpura; less commonly - superficial erosions, bullae, urticaria Associated Read more [...]

Takayasu’s Arteritis

Synonyms: Aortic arch syndrome, pulseless disease, aortitis syndrome, occlusive thromboaortopathy. ICD-9 Code: 446.7 ICD-10 Code: M31.4 Definition: Takayasu’s arteritis is a large vessel vasculitis of the aorta and its branches resulting in vascular ischemia. Etiology: Takayasu’s arteritis is associated with HLA Bw52 in >40% of afflicted individuals. Circulating antiarterial antibodies have been investigated as putative etiologic agents. Pathology: Granulomatous panarteritis results Read more [...]

Macrophage Activation Syndrome (MAS)

Synonyms:  Hemophagocytic syndrome,  hemophagocytic lymphohistiocytosis (HLH), histiocytic erythrophagocytosis ICD-9 code:  288.4 ICD-10 codes: Macrophage activation syndrome D76.1;  Hemophagocytic syndrome, infection-associated D76.2 Definition: MAS is a severe, potentially fatal disease characterized by severe systemic inflammation. In the bone marrow and other lymphoid tissue a characteristic finding in hemophagocytosis. Etiology: MAS relates to abundant inflammation driven Read more [...]

Systemic Lupus Erythematosus (SLE)

Synonyms: Lupus, lupus erythematosus, SLE ICD-9 Codes: SLE 710.0; discoid, 695.4; lupus anticoagulant 286.5; drug-induced lupus 695.4; lupus nephritis 583.81. ICD-10 Codes:  SLE M32; discoid L93.0; subacute cutaneous lupus L91.0;  lupus anticoagulant syndrome D68.62; antiphospholipid syndrome D68.61;  drug-induced lupus, M23.0; lupus nephritis M32.14 Definition: SLE is a systemic autoimmune disease characterized by autoantibody production, inflammation, and tissue damage that can affect Read more [...]


Synonyms: SpA; seronegative SpA; spondyloarthropathy, HLA-B27-related SpA. NB. The preferred terminology has ICD-9 Codes: Spondyloarthropathy/Spondylitis, 720.9; Codes for individual disorders: AS,  720.0; reactive arthritis / Reiter ’s syndrome, 099.3; psoriatic arthritis, 696.0. ICD-10 codes: Spondyloarthopathy/spondyloarthritis M45-M49; Ankylosing spondylitis M45; reactive arthritis/Reiter's syndrome M02.3; juvenile ankylosing spondylitis M08.1 Definition: SpA is a generic term applied Read more [...]

Granulomatosis with Polyangiitis (GPA)

Synonyms:  GPA, Wegener's granulomatosus ICD-9 Code: 446.4. Definition: Granulomatosis with polyangiitis (GPA) is a vasculitic syndrome associated with upper respiratory, pulmonary, and renal involvement. It is characterized histologically by necrotizing granulomatous vasculitis of small arteries and veins. Etiology: Although it has long been suspected that GPA relates to exposure to some environmental agent, none has been implicated.  There is no evidence of immune complex disease. Read more [...]

Fever and Arthritis

ICD-9 Codes: Definition:  The chapter considers conditions that manifest prominent fever and oligo- or polyarthritis. Polyarthritis is defined as inflammatory joint pain with swelling (synovial proliferation or effusion) affecting 4 or more joints. Oligoarthritis affects 3 or fewer joints and is usually asymmetric in distribution. Fever should be greater than 101 F, the duration of which depends on the condition.  The presence of fever is distinctive as most oligo- or polyarticular conditions Read more [...]

Autoimmune Hepatitis

Synonyms: AIH, Lupoid hepatitis, chronic active hepatitis, plasma cell hepatitis ICD-9 code: 571.42; ICD-10 code:  K75.4 Definition: Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disorder of unknown etiology characterised by hepatocellular inflammation, tranaminitis and distinctive autoantibodies. Pathology:  Liver biopsy should be obtained early to establish histologic severity and guide therapy.   Characteristic histology includes a lymphoplasmacytic periportal infiltration. Read more [...]

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