Last updated: October 17, 2014

Trade Names: Lodine, Lodine XL

Synonyms: Etodolic acid

Drug Class: NSAID

Capsules: 200- and 300 mg
Tablets: 400- and 500 mg
Tablets, extended release (XL): 400-, 500-, 600 mg

Dose: 200–400 mg two or three times daily; doses above 1000 mg/day have not been adequately evaluated. Extended release 400–1,000 mg once daily.

Clinical Pharmacology: Well absorbed after oral administration; hepatic metabolism and renal excretion of metabolites; half-life 7 hours

Comments: Compared with traditional, older NSAIDs, somewhat COX-2 “preferential”

Cost: $$$

See NSAIDs for Indications, Mechanism of Action, Contraindications, Precautions, Monitoring, Pregnancy Risk, Adverse Effects, Interactions, and Patient Instructions.


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