Last updated: October 20, 2014
Trade Names: Aleve (OTC), Anaprox, EC-Naprosyn, Naprelan, Naprosyn
Synonyms: Naproxen sodium
Drug Class: NSAID
Tablets: 250, 375, 500 mg
Tablets (enteric coated): 375 and 500 mg
Tablets, as sodium (Anaprox): 275 mg (250 mg base), 550 mg (500 mg base).
OTC: 220 mg (200 mg base)
Oral suspension: 125 mg/5 mL
Dose: 500–1,000 mg/day in two divided doses
Clinical Pharmacology: Well absorbed after oral administration; hepatic metabolism; renal elimination. Half-life is 13 hours.
Cost: OTC (low dose), $; generic, $$
See NSAIDs for Indications, Mechanism of Action, Contraindications, Precautions, Monitoring, Pregnancy Risk, Adverse Effects, Interactions, and Patient Instructions.